Liver Fibrogenesis in Non-Alcoholic Steatohepatitis

Liver Fibrogenesis in Non-Alcoholic Steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) is emerging as one of the most common chronic liver diseases in developed western countries. Non-alcoholic steatohepatitis (NASH) is the most severe form of NAFLD, and can progress to more severe forms of liver disease, including fibrosis, cirrhosis, and even hepatocellular carcinoma. The activation of hepatic stellate cells plays a critical role in NAS...

[Non-alcoholic fatty liver disease and non-alcoholic steatohepatitis].

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are the hepatic manifestations of the metabolic syndrome. Since the prevalence of obesity and consequently of the metabolic syndrome is steadily increasing, the different types of NAFLD are nowadays the most common cause of liver injury in North America. The development of NASH and fatty liver cirrhosis occurs af...

Current solutions for obesity-related liver disorders: non-alcoholic fatty liver disease and non-alcoholic steatohepatitis.

o besity is a worldwide epidemic with more than 1 billion overweight adults and at least 300 million obese patients [1]. According to recent statistics from the United States, 16.9% of children and adolescents aged 2–19 years were obese in 2009–2010 and 31.8% were either overweight or obese [2]. The rise in childhood obesity has been accompanied by an increase in pediatric liver diseases: 70%–8...

Non-alcoholic steatohepatitis

The Correlation between Serum Zinc Level and Liver Histology in Non-Alcoholic Steatohepatitis

Background & Objective: The aim of this present study was to assess the relationship between serum zinc levels and liver histopathological findings in non-alcoholic steatohepatitis (NASH) patients.Methods: This case-control study was performed in consecutively selected NASH patients who had been referred to a general hospital. The control group consisted ...